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Frekil Herald

Stop asking. Let the data tell.

94% of adverse drug reactions go undetected by spontaneous reporting. In the Vioxx case, the signal was in the data 3.5 years before the drug was pulled. Herald continuously scans millions of patient records for safety, efficacy, and commercial signals — and makes sure that doesn't happen again.

Safety Signal
Efficacy Gap
Switching Event
Herald Active

What changes.

Before Herald
With Herald
A clinician notices a pattern after 5 years of practice
Herald detects the same pattern across 2M patients in 6 months
94% of adverse reactions go undetected by spontaneous reporting
Active surveillance across your entire patient population
Months to answer a single safety or efficacy question
Signals surfaced in days across millions of records
Episodic studies, run once or twice a year
Continuous monitoring, updated as new data flows in

What Herald actually monitors.

Safety, effectiveness, commercial, and health economic signals. Simultaneously. Across your entire real-world patient population.

Safety

Detection Targets
  • ADRs missed by spontaneous reporting
  • Drug-drug interactions from real-world co-prescribing
  • Population-specific safety profiles
  • Long-term emerging risks
Why It Matters

Catch safety signals years before spontaneous reporting surfaces them. Act on risk before it becomes a public crisis.

Effectiveness

Detection Targets
  • Comparative effectiveness vs. alternatives
  • Subpopulation response differences
  • Treatment sequence optimization
  • Real-world vs. trial efficacy gaps
Why It Matters

Know exactly where your drug wins and where it doesn’t, broken down by subpopulation. Updated continuously, not once a year.

Commercial

Detection Targets
  • Off-label prescribing patterns
  • Treatment switching and discontinuation rates
  • Market share shifts by geography and payer
  • Medication adherence trends
Why It Matters

See label expansion opportunities, competitive threats, and prescribing shifts as they happen. Not in next quarter’s report.

Health Economic

Detection Targets
  • Healthcare resource utilization changes
  • Total cost of care trajectories
  • Readmission rate patterns
  • Downstream cost savings
Why It Matters

Build your value-based contracting evidence in real-time. Walk into payer negotiations with data from last week, not last year.

Stop asking the data.
Let the data tell you.

Deploy Herald on your existing data infrastructure. Surface signals your competitors won't see for years.